butabarbital will decrease the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
fentanyl intranasal and diazepam each boost sedation. Stay away from or Use Alternate Drug. Limit use to people for whom alternative procedure choices are insufficient
mitotane decreases levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Mitotane is a powerful inducer of cytochrome P-4503A4; watch when coadministered with CYP3A4 substrates for probable dosage adjustments.
Concomitant use of benzodiazepines, together with diazepam, and opioids may possibly cause profound sedation, respiratory melancholy, coma, and Demise; reserve concomitant prescribing of benzodiazepines and opioids to be used in individuals for whom substitute treatment possibilities are inadequate; minimize opiate dose a person-third when diazepam is additional
enzalutamide will minimize the extent or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
iloperidone will increase amounts of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Iloperidone is a time-dependent CYP3A inhibitor and could bring about increased plasma amounts of medicine predominantly removed by CYP3A4.
Reserve concomitant prescribing of those medications in patients for whom other treatment selections are inadequate. Limit dosages and durations to the minimal required. Observe closely for indications of respiratory despair and sedation.
Am i able to drink Alcoholic beverages while using diazepam? Do not consume Liquor although you're taking diazepam. Liquor can raise the effects of diazepam. It could make you go into a really deep sleep. There is a threat you will not be able to breathe adequately, and you might have difficulty waking up.
oxcarbazepine will decrease the extent or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Oral: Information not offered No dose adjustment encouraged Except administered for prolonged time period; minimize dose in extended intervals
Continually keep track of very important signals throughout sedation and recovery period of time if coadministered. Very carefully titrate remimazolam dose if administered with opioid analgesics and/or sedative/hypnotics.
ceritinib will enhance the stage or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
diazepam will boost the degree or result of midazolam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Coadministration of gentle get more info CYP3A4 inhibitors with midazolam intranasal may possibly result in higher midazolam systemic publicity, which may prolong sedation.
drospirenone will enhance the amount or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.